Bicuspid Valve-Related Aortic Disease

Bicuspid aortic valve disease.

Bicuspid aortic valve (BAV) disease is the most common congenital cardiac defect. While the BAV can be found in isolation, it is often associated with other congenital cardiac lesions. The most frequent associated finding is dilation of the proximal ascending aorta secondary to abnormalities of the aortic media. Changes in the aortic media are present independent of whether the valve is functio...

Aortic dilatation in bicuspid aortic valve disease.

Bicuspid aortic valve (BAV) is the most common congenital cardiac abnormality, occurring in 0.5%-1.4% of the population; this anomaly is sporadically transmitted genetically by an autosomaldominant pathway, with a 3:1 male predominance. BAV is clinically important, not only because of valve-related complications (valve dysfunction, infective endocarditis), but also because of its association wi...

Genetics of Bicuspid Aortic Valve and Calcific Aortic Valve Disease

The bicuspid aortic valve and related disorders.

Bicuspid aortic valve (BAV) is the most common congenital cardiac malformation, affecting 1-2% of the population, with strong male predominance. Individuals may have a normally functioning BAV, and may be unaware of its presence and the potential risk of complications. However, they may easily develop aortic valve disorders: either stenotic or regurgitant, or both. Today, BAV is recognized as a...

Bicuspid Aortic Valve Disease: A Comprehensive Review

Bicuspid aortic valve is the commonest congenital cardiac abnormality in the general population. This paper article will discuss our current knowledge of the anatomy, pathophysiology, genetics, and clinical aspects of bicuspid aortic valve disease.